Endocrine Abstracts

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.Case report: A 65-year-old male, with significant cardiac and pulmonary pathology, diagnosed with type 2 diabetes since 1996 and treated with glargine (70 U/day) and aspart (68 U/day) insulin is admitted to our centre via ER (emergency room) after an episode of...

Intentional insulin overdose in diabetic patients is a rare critical situation. The severity is due to numerous neurological complications, electrolyte disturbances, liver and lung damage or death.A 76-years old female, with significant cardiac pathology, diagnosed with type 2 diabetes and treated with Humalog Mix50® 0-0-24 U/day, is admitted to our center via ER (emergency room) after an episode of severe hypoglycemia after administratio...

Upper extremity deep vein thrombosis (UEDVT) is not infrequent and accounts for approximately 14% of deep vein thrombosis. The risk of pulmonary embolism is lower than in lower extremity DVT and prompt diagnosis is essential to select those patients who deserve anticoagulant treatment. Previous studies indicated that type 2 diabetes (DM) patients carried greater risk of DVT development or recurrence than the general population.A 49-years old female, with...

Polyglandular autoimmune syndromes (PAS) are a heterogeneous group of rare diseases characterized by autoimmune activity against more than one endocrine organ, although non-endocrine organs can be affected. In PAS III, autoimmune thyroiditis occurs with another organ-specific autoimmune disease, but the syndrome cannot be classified as PAS I or II.A 29-years old man was refer to our center for diagnostic confirmation with the following complaint...

Introduction: Type 1 diabetes mellitus (T1DM) is the most common form of diabetes in children and young adults. Though T1DM often presents in an acute manner, it may be preceded by a prodromal period, often extending over years.Case report: A 19-year-old male, diagnosed with T1DM at the age of 15, with no insulin treatment, was admitted to our department for high glycemic value (G) of 365 mg/dl on a routine exam at his GP. At diagnosis the patient was as...

In type 1 diabetes athletes, the proper adjustments of insulin doses and carbs intake are essential in order to avoid a hypoglycemic event that could affect the sport performances.The aim of the study was to assess the risk of hypoglycemia, the insulin and glycemic variability in 2 different days (with and without physical activity) in a group of nine players with type 1 diabetes, members of the Romania diabetes futsal team (twice European champion)....

Nesidioblastosis is defined as a diffuse proliferation of primitive pancreatic islet cells budding from ductal epithelium. This condition can cause hypoglycaemia in infants as a result of mutations in the sulfonylurea receptor or in the anatomically linked potassium channel. In adults, this disease occurs independently from these genetic mutations.Case report: A 41-year-old male was referred to our center via emergency room with suspicion of an insulinom...

Introduction: Bulimia is an eating disorder characterized by constant preoccupation with food, irresistible cravings for food and binge eating episodes. The data regarding the incidence of bulimia in people with diabetes are contradictory. The glycemic variations subsequent to binging and vomiting leads to complications like retinopathy, kidney or liver failure, hypoglycemic comas and electrolyte imbalances.Case presentation: A 57-year-old female, diagno...

Introduction: Pain in the groin area is frequently encountered in football players, the cause being a sport hernia, muscle tears, avulsions, sacroiliac joint pathology, etc. Local corticosteroid injections (LCIs) are often used as one of the first-line treatments in the conservative management because of their ease of delivery, low cost and efficacy.Case presentation: A 32-year-old amateur futsal player (goalkeeper) diagnosed with type 1 diabetes at the ...

Background: Adequate and appropriate nutrition in type 1 diabetic athletes is essential not only to increase the physical performance but also to prevent the hypoglycemic events. Detailed nutrition history represents the initial step in developing a proper meal plan according to the specific characteristics of the physical activity performed.Purpose: This study assessed changes in habitual dietary intake and macronutrient distribution in response to inte...